TURKU Metabolomics Facility, Finland
"We use the LECO Pegasus BT instrument for the quantiﬁcation of small polar metabolites. We developed a hybrid method where we quantitate 51 metabolites with standard curves and screen for any other small polar metabolites in a wide range of biological samples. This assay has a great dynamic range thanks to the sensitivity of the BT. The StayClean® ion source allows us to run hundreds of samples in a batch and be conﬁ dent that the ion source will remain clean even with dirty samples such as plasma."